- Obregon, Juan (from Venezuela, Obregon Music, Obregon hand move)
- Obrero
- Obrint Pas
- OBS (German DJ duo)
- Obscenity (German death metal band)
- Obscenity Trial
- Obscura (technical death metal band from Munich, Germany)
- Obscura Qalma (Symphonic death metal from Venice, Italy)
- Obscura Religio
- Obscurcis Romancia
- Obscure (Pioneer in Bangladesh)
- Obscure Anachronism
- Obscure Disorder
- Obscure Sphere
- Obscure Sphinx
- Obscure, The
- Obscurity (Swedish death metal band)
- Obscurity (Black/Viking metal band from Germany)
- Observatory, The (US rock band from Athens, Georgia)
- Observatory, The (Singaporian space rock)
- Observe & Control
- Observer Drift
- Obsessed, The (doom metal music)
- Obsession (UK dance remakes for Almighty Records)
- Obsession (American metal)
- Obsessive
- Obsessives, The
- Obsidia (Dubstep/Dubstyle/Drum & Bass/Electronic Producer from the UK)
- Obsidian Kingdom
- Obsidian Mind
- Obsidian Shell
- Obsidian Shrine
- Obsidian Tide
- Obsidian Tongue
- Obsidiots
- Obsidious
- Obskür
- Obskür (Obskür)
- Obskure Torture
- Obsolescence
- Obsolete Humanity (Belgian death/groove metal band)
- Obsolete Theory
- Obsoletos
- Obstrukt
- OBSYDIA (NIJISANJI EN VTuber group)
- Obtained Enslavement
- Obtest
- Obukuro, Nariaki
- Obús
- obylx
- Obywatel G.C.
- OC Hermo
- OC Times (Barbershop Quartet)
- OC, Charlotte (Singer)
- Ocaklı, Erkan
- Öçal, Burhan & Trakya All Stars, The
- Ocaña, Chico
- Ocasek, Ric
- Occams Laser
- Occidens
- Occult (Dutch thrash metal band)
- Occult (Dutch Death/Thrash Metal band)
- Occult Hand Order
- Occultation
- Occults
- OCD (Philadelphia rap duo)
- Oceaán (Brussels-born Manchurian electronic music producer)
- Oceán (Czech electronic group)
- Ocean (US gospel rock band from the 1970s)
- Ocean (Swiss soft rock and folk rock band)
- Ocean (Polish Rock Band)
- Ocean Alley
- Ocean Blue, The (American indie pop)
- Ocean Chief
- Ocean Colour Scene
- Ocean Drive
- Ocean Drive feat. Oriska, DJ
- Ocean Flaws
- Ocean Grove (Australian nu metal band)
- Ocean Grove (United States)
- Ocean Grove feat. Dune Rats
- Ocean Grove feat. lil aaron
- Ocean Is Theory
- ocean jams
- Ocean Jet
- Ocean Kelly (Rapper, Legendary Icon)
- Ocean Music
- Ocean of Grief
- Ocean Park Standoff
- Ocean Party, The
