- Original Deutschmacher, Die
- Original Dixieland Jazz Band
- Original Flavor ('90s US rap group)
- Original God
- Original God & LIL NARNIA
- Original Gros Bonnet
- Original Lead Singers of The Temptations, The
- Original London Cast
- Original London Cast of Girl From The north Country
- ORIGINAL LOVE
- Original Memphis Five
- Original Mirrors
- Original Motion Picture Soundtrack
- Original Naabtal Duo
- Original Pistols, The
- Original Rudeboys, The
- Original Sin (UK drum and bass)
- Original Südtiroler Spitzbuam
- Original Swimming Party
- Original Television Cast of Hairspray LIVE!
- Original Uman
- Original Zillertaler (Folk, Pop)
- Original, The (electronic/house group)
- Originale, Die
- Originale, Ragz
- Originale, Ragz feat. Glacier, John
- Originales de San Juan, Los
- Originals, The (Motown group)
- Originoo Gunn Clappaz
- Origo (Epidemic Sound)
- Orikasa, Fumiko
- ORIO (hololive vtuber duo)
- Oriol, Christiane (French singer & songwriter)
- Orioles, The
- Orion (Symphonic Prog Group from France)
- Orion (Cybernetic Noir)
- Orion Experience, The
- Orion Riders
- orion sun
- Orion the Hunter
- Orion Too (Belgian 2000s trance project)
- Orion Too feat. Caitlin
- Orión XL (Argentine Rapper)
- Orion, DJ (Electro/Cumbia)
- Orion's Reign
- Orionix
- Orions Belte (Norwegian instrumental band)
- Orions Belte feat. Aase, Sigrid
- Orishas (cuban hip hop group)
- Orishas feat. Buenaventura, Yuri
- Orishas feat. Niko Noki
- Orishas feat. Passi
- Orixa
- Orka
- Orkan (Swedish prog rock)
- Orkest
- Orkest Zonder Naam
- Orkesta Mendoza (Indie Mambo)
- Orkhan Efendi
- ORKID (Swedish singer)
- Orkidea (Finnish DJ / producer Tapio Hakanen)
- Orkiestra Dni Naszych
- Orko (UK rock band)
- Orko the Sycotik Alien
- Orkrist
- Orlandi, Violet
- Orlando (Belgian tech house singer)
- Orlando (Italian italo-dance project)
- Orlando Julius (Nigerian saxophonist, singer, bandleader, and songwriter)
- Orlando Marin & His Orchestra
- Orlando Philharmonic Orchestra
- Orlando Pops Orchestra
- Orlando Riva Sound
- Orlando Vera Cruz
- Orlando, Bobby (US record producer, indie record label owner, songwriter & musician)
- Orlando, Courtney (singer-songwriter, FKA J.R.)
- Orlando, Johnny (Canadian singer-songwriter, vlogger and actor)
- Orlando, Johnny (reggae artist)
- Orlando, Johnny & BENEE
- Orlando, Johnny & kenzie
- Orlando, Ramón
- Orlando, Tom (artist from Ottawa, Ontario, Canada)
- Orlando, Tony
- Orlando, Tony & Dawn (1970s pop group)
- Orlane
- Orleans
- Orlek
- Orleya
- Orlik (czech Oi!)
- Orloff, Peter
