- Oscar and the Wolf
- Oscar Basza
- Oscar Blesson (Norwegian Rapper)
- Oscar de Fontana
- Oscar de la Hoya
- Oscar Emch
- Oscar G. and Falcon, Ralph
- Oscar Hammerstein II and Richard Rodgers
- Oscar Medina
- Oscar Peterson (Oscar Peterson)
- Oscar the Grouch (Sesame Street Muppet)
- Oscar, Alexander
- Oscar, Brad
- Oscarcito (Oscar Hernández)
- Oscenrad
- Oscher, Paul
- Oschino
- Oscillation, The (UK drone ambient rock)
- Oscillian (Synthwave from Sweden)
- Oscillian feat. Nina
- Osdorp Posse
- Osdorp Posse & Nembrionic
- Ose
- Osees (use also for Thee Oh Sees and Oh Sees)
- Osenga, Andrew
- Oshea
- oshi (producer)
- Oshiego (Singaporean Death/Thrash Metal)
- Oshima, Michiru (Japanese anime, film, TV & video game composer)
- Oshio, Kotaro
- Osho Jain
- Osho, Josh
- Osho, Josh & Childish Gambino
- Osho, Josh & Ghostface Killah
- Oshota
- OSHUN (female hip hop duo)
- Oshun (1960s musician)
- OSI (progressive rock band)
- Osi and the Jupiter
- Osiah
- Osibisa
- Osiecka, Agnieszka
- Osińska, Dorota
- Osiris (undisambiguated)
- Osiris (US funk band)
- Osiris (Progressive Rock band from Bahrain)
- Osiris Wolf
- Osiris, YK
- Osiris, YK feat. Kehlani
- Osiris, YK feat. Russ
- Osiris, YK feat. Snoop Dogg
- Osirus Jack (667 crew)
- Oska (Maria Burger, singer-songwriter from vienna)
- Oska (DJ/Producer from Israel)
- Oskar (Ognjen Amidzic)
- Oskar
- Oskar Cyms
- Oskar, Griffin
- Oskar, Lee
- Oskee, Tay
- Osker
- Oski (Australian DJ & producer)
- OSKI (Belgian rapper & producer Oscar Santos)
- Oskord
- Oskorri
- Oskr
- Oslender, Simon (Keyboardist from Aachen, Germany)
- Oslin, K.T.
- Oslo (lo‐fi beatmaker)
- Oslo Ess
- Oslo Gospel Choir
- Oslo Ibrahim
- Oslo Parks
- Oslo Soul Children
- Oslo Tropique (French rock band)
- Osman
- Osment, Emily
- Osmi putnik
- Osmik
- Osmo
- Osmo's Cosmos
- Osmond Brothers
- Osmond, David
- Osmond, Donny
- Osmond, Donny & Marie
- Osmond, Donny & Wonder, Stevie
- Osmond, Donny & Wright, Laura
- Osmond, Jimmy
- Osmond, Little Jimmy
- Osmond, Marie
