- Orquesta Sinfónica Nacional de Costa Rica
- Orquesta Sublime
- Orquesta Tabaco y Ron
- Orquesta Típica Fernández Fierro
- Orquesta Típica Misteriosa Buenos Aires
- Orquesta Todos Estrellas (Cuban orchestra (All Stars) with various artists from Egrem label)
- Orquesta Zodiac
- Orquestra Afro-Brasileira
- Orquestra Brasileira de Música Jamaicana
- Orquestra Contemporânea de Olinda
- Orquestra Imperial
- Orquestra Voadora (Brazilian brass band)
- Orquestra Was
- Orr, Benjamin
- Orr, David
- Orrall, Robert Ellis (US country singer/producer)
- Orrantia, Hayley (US actress and singer)
- Orrason, Máni
- Orrico, Stacie
- Orrje, Carl, Piano Ensemble
- Orry Jackson (German singer and songwriter)
- Orsa spelmän
- Orselli, Folco
- Orsen, Jack
- Orsen, Jack & Taktloss
- Orsenna, Erik
- Orsi
- orso, L' (Italian band)
- Orsolics, Hans
- Orson (00s US power pop band)
- Orsons, Die
- Orsons, Die feat. Cro
- Orsons, Die feat. Maxim
- Örsten
- Orta, Choco
- Orta, Manuel
- Orta, María (Puerto Rican Christian music singer)
- Orta, Paul
- Ortaç, Serdar
- Ortaçgil, Bülent
- Ortaçgil, Bülent & Teoman
- Ortak, Svaba (rapper from Austria)
- Ortega, Anthony (jazz saxophonist)
- Ortega, Anthony, Trio
- Ortega, Emanuel
- Ortega, Fernando
- Ortega, Jeannie
- Ortega, Jeannie feat. Papoose
- Ortega, José (designer)
- Ortega, Lindi
- Ortega, Michael
- Ortega, Paco
- Ortega, Palito
- Ortelli, Paolo, Matrix, DJ, Party Boomers feat. C, Jay
- Ortero, David
- Orth, Marisa
- Orthentix
- Orthodox (Spanish doom metal)
- Orthodox (Straight Edge)
- Orthodox Celts
- Orthostat
- Orties
- Ortiga (Chilean canto nuevo group)
- Ortiga (Former Esteban & Manuel member)
- Ortiz, Alfredo (player of the Paraguayan harp)
- Ortiz, Bill
- Ortiz, Gerardo (Regional Mexican singer)
- Ortiz, Joell (rapper fka Jo‐ell Quikman)
- Ortiz, Joell feat. Fat Joe
- Ortiz, Joell feat. Novel
- Ortiz, Kevin
- Ortiz, Luis “Perico”
- Ortolani, Riz
- Ortolani, Riz feat. Ranieri, Katyna
- Orton, Beth
- Orton, Beth feat. Callier, Terry
- Orton, Mark
- ortoPilot
- Ortsul (Poland / Black Metal)
- Oruç, Mustafa
- Orup (Swedish musician Hans Thomas Eriksson)
- Örvarsson, Atli (Icelandic score composer)
- Orville Peck
- Orvokki
- Orwell (French band)
- Orwells, The
- Orxata Sound System
- Ory, Kid
- Oryad (doom metal/symphonic metal group)
- Oryema, Geoffrey
