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- SweSwi
- SwiSwi
- SwiSwo
- SwoSyl
- SylSym
- SymSyr
- SyrSz
- SzuSzy
- Sebastian, John
- Sebastian, John and the J Band
- Sebastian’s Filthy Goo
- sebastian6 (Gabriel O’Leary)
- Sebastianelli, Olivia
- Sebastien (Czech metal band)
- Sébastien Chato
- Sebastien feat. Hagedorn
- Sebastien feat. Lynch, Michael
- Sebastien feat. OVI
- Sebastien feat. Satellite Empire
- Sebastien Grainger & The Mountains
- Sébastien, Patrick
- Sebastopol (UK indiepop band)
- Sebel (Sebastian Niehoff)
- SEBELL (Canadian indie pop male vocalist)
- seBENTA (Portuguese rock band)
- Sebesky, Don
- Sebestyén, Márta
- Sebghati, Houman
- Sebia (Greek hard rock group)
- SEBii (hyperpop producer/rapper from Shanghai)
- Sebina, Mpho
- Sebjak
- Sebó (Sebastian Bosum)
- Sebo & Madmotormiquel & Nayan Soukie
- Sebo & Madmotormiquel & Soukie, Nayan
- Sebutones
- Secada, Jon
- Secada, Jon · Pavarotti, Luciano
- Secada, Jon & Pavarotti, Luciano
- Secada, Jon & Shanice
- Secada, Jon and Shanice
- Secchi
- Secchi, Stefano
- Secession
- Secession, The
- Sech
- Sech feat. Mozart la Para & Farina
- Sechem
- SECHSKIES
- Seck, Cheick Tidiane
- Seck, Djeneba
- Seck, Thione
- Seckond Chaynce
- Secluded, The (rock band)
- Secoli Morti
- Secombe, Harry
- Second (Spanish band)
- Second Act (key track: 'Natural High')
- Second Band, The
- Second Chance Blown
- Second City
- Second Civil (Artis SMM Records)
- Second Class
- Second Combat
- Second Come (Brazilian band)
- Second Coming (US rock/industrial band)
- Second Coming (hardcore, ca, usa)
- Second Coming, The (early incarnation of "The Allman Brothers Band")
- Second Date
- Second Decay (German wave band)
- Second Identity (A-lusion & Scope DJ)
- Second Layer
- Second Person
- Second Sex
- Second Still (gothic rock)
- Second Sun
- Second Sun (Progressive psychedelic trance project based in Denmark)
- Second Thief
- second thoughts (British indie pop group based in Hitchin)
- second thoughts & House Pet
- Second to Sun
- Second Voice
- Second-Hand Apes
- Seconday (Bulgarian rock band)
- Secondcity
- Secondcity & Rowe, Tyler
- Secondcity feat. Love, Ali
- Secondhand Serenade
- Secondhand Serenade feat. Ballestrini, Veronica
- Secondhand Sound
- Seconds Before Landing (US Prog Group)
- Seconds Flat
- Secondshot (Punk Rock Band)
- Secondspring
- Secondtunez
- Secondwall
- Secos & Molhados
- Secret
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