- SS
- SSaa
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- SAFSah
- SahSai
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- SNASna
- SnaSno
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- SoeSof
- SofSOJ
- SOJsol
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- stoSto
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- sweswe
- SweSwi
- SwiSwi
- SwiSwo
- SwoSyl
- SylSym
- SymSyr
- SyrSzt
- SzSzy
- Schygulla, Hanna
- Schyman, Garry
- Schytts
- Sci-Clone
- Sci-Fi SKANE
- Scialfa, Patti
- Scialpi
- Scianari, I
- Scibilia, Marc
- Science (house/breaks)
- Science Department
- Science for Girls
- Science of Sleep
- Science, The
- Science!
- Scientist (Jamaican dub producer Hopeton Brown)
- Scientist (experimental/sludge/post metal band from Chicago, IL)
- Scientists, The (post‐punk band from Perth, Australia)
- Scienz of Life
- ScienZe (rapper)
- Ścigani
- Scila (Spanish groove metal band)
- Scimeca, Nicole & Peil, Mary Beth
- Scimitar (Victoria, BC melodic death/pagan metal band)
- Scintii (Stella Chung)
- Scintilla, Kalya
- Scipione, Umberto (Italian score composer)
- Scirocco (Luca d'Agostino Italian folk rock artist)
- Scisma
- Scissor Sisters
- Scissor, Ed feat. Contact Play
- Scissorfight
- Scissors for Lefty
- Scissors, The (pop punk band from Chicago)
- Sciuto, Tony
- Scky Rei
- SCNDL
- scntfc
- scntfc & Tettix
- Scobell, Pete, Band
- Scobey, Bob
- Scocco, Mauro
- Scoff (Germany)
- Scofield, John
- Scofield, John & Metheny, Pat
- Scofield, John & Ritenour, Lee
- Scollo, Etta
- Scone Cash Players
- Scontati, Gli
- Scoob & Sydney
- Scoobert Doobert
- Scooby (US rapper)
- Scooch
- Scoop (Belgian late 1990s trance duo)
- Scooped Up!
- Scooter (German dance/rave band)
- Scooter (80s Belgian group, key tracks "You", "Minute By Minute")
- Scooter & Dave 202
- Scooter & FiNCH
- Scooter & Harris & Ford
- Scooter & Jebroer
- Scooter & Ottaviani, Giuseppe
- Scooter & Timmy Trumpet
- Scooter & Vassy
- Scooter & Xillions
- Scooter and Vassy
- Scooter Brown
- Scooter feat. Leandros, Vicky
- Scooter Feat. Leandros, Vicky
- Scooter feat. Maidwell, Michael
- Scooter feat. Wiz Khalifa
- Scooter vs. Acardipane, Marc & Rules, Dick
- Scooter vs. Status Quo
- Scooter x FiNCH
- Scooter x Xillions
- Scope (1990s Indonesian group)
- Scope DJ (hardstyle dj)
- Scorch, Al
- Scorched Oak
- Scorched Vatika
- Scorched Waves
- Scorched-Earth (duplicate)
- Scorched-Earth (US death metal band from Seattle)
- Scorcher (UK Grime MC and producer)
- Score, The (The Score formed in 2007 as the band of Arison Cain)
- Score, The (Eddie Anthony & Edan Dover, formed in NY, moved to LA, CA)
- Score, The & AWOLNATION
- Score, The feat. FITZ
- Score!
- Scorefor
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