- SS
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- SahSai
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- SloSLU
- SLUSma
- SmaSmi
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- SNASna
- SnaSno
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- SurSut
- SutSva
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- SwaSwe
- SweSwe
- SweSwi
- SwiSwi
- SwiSwo
- SwoSyk
- SyKSym
- SymSyn
- SYNSzh
- SziSzy
- Scotty (German house/trance artist)
- Scotty (US rapper)
- Scotty Cain
- Scotty Don't
- Scotty Vanity
- Scoundrel (Sheffield)
- Scoundrels (London blues rock band)
- Scoundrels (Dutch 1980s punk band)
- Scourger, The (Finnish thrash metal band)
- Scout (New York indie rock band)
- Scouten, Sarah Jane (Canadian folk musician)
- Scouting for Girls
- Scoutmaster
- Scowl (Santa Cruz hardcore band)
- Scøtt, Jay (Quebec)
- Scrabbel
- Scracho
- Scram C Baby
- Scram Jones
- Scrap Arts Music (from British Columbia, Canada)
- Scrap Pile (US Death Metal)
- Scrap Worthy
- Scraping Foetus Off the Wheel
- Scraps of Tape
- Scratch (US human beatboxer Kyle Jones)
- Scratch Acid
- Scratch Bandits Crew
- Scratch Bandits Crew feat. Taiwan MC & Youthstar
- Scratch Massive
- Scratch Massive feat. Chloë
- Scratch21
- Scratching Post
- Scratchy Blanket
- Scraton
- Scrawny
- Scream (USA punk band)
- Scream (Swiss pop rock band)
- Scream Machine (industrial)
- Scream Maker (heavy metal)
- Scream of the Butterfly
- Scream Silence
- Scream, DJ (US hip-hop mixtape DJ)
- Scream, The (US hard rock band)
- Screamer (Swedish heavy metal band)
- Screamers, The (synthpunk)
- Screamfeeder
- Screamin' Whisper
- Screamin’ Cheetah Wheelies
- Screaming Blue Messiahs, The
- Screaming Dead
- Screaming Eagles (Northern Irish Hard Rock Band)
- Screaming Females
- Screaming Glasses, The
- Screaming Headless Torsos
- Screaming Jets, The
- Screaming Mechanical Brain
- Screaming Orphans
- Screaming Skulls, The
- Screaming Trees (Washington grunge band)
- Screaming Trees (80s UK industrial/EBM duo)
- Screaming Tribesmen, The
- Screams for Tina
- Screams of Erida
- Screams of Hockomock
- Screams, Mercy
- Scred Connexion
- Screech Boys, The
- Screeching Weasel
- Screed
- Screen Frogs
- SCREEN mode
- Screen Vinyl Image
- ScreenAge
- Screenshots, The
- SCREW (Japanese visual kei, 2006~2016)
- Screw 32
- Screw, DJ (US "screw" rap DJ/producer)
- Screw, DJ feat. E.S.G.
- Screw, DJ feat. Point Blank
- Screwball (QB hip hop group)
- Screwball feat. Capone
- Screwball feat. M.O.P.
- Screwball feat. Matrix Bars
- Screwball feat. Nature
- Screwed Up Click
- Scriabin, Alexander Nikolayevich (pianist and composer)
- Scribe (New Zealand rapper Malo Luafutu)
- Scribe (Indian Heavy Metal band)
- Scribe feat. Ladi6
- Scribe feat. Savage & Con Psy
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