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- SwiSwo
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- SydSyl
- SymSyn
- SynSyr
- SyrSz
- Szpszy
- Simone (Brazilian Artist)
- Simone (Austrian Schlager singer Simone Stelzer)
- Simone & Duncan, Zélia
- Simone & Nascimento, Milton
- Simone & Simaria
- Simone & Simaria & Bruno & Marrone
- Simone & Simaria & Tierry
- Simone & Simaria feat. Anitta
- Simone & Simaria feat. Jorge & Mateus
- Simone Carpet
- Simone Fedi
- Simone Jay
- Simone, Afric
- Simone, Alina
- Simone, Dominique
- Simone, Franco
- Simone, Frankie
- Simone, Lisa (vocal jazz singer, daughter of Nina Simone)
- Simone, Margaux
- Simone, Nina (US singer, songwriter, pianist, arranger and civil rights activist)
- Simone, Nina & Corry, Joel
- Simone, Nina & Sofi Tukker
- Simone, Raz (Seattle hip-hop artist)
- Simone, Seraphina
- Simone, Zola
- Simonec, Tim
- Simonet, Manolito y su Trabuco
- Simonett, Dave (Trampled By Turtles’ lead vocalist and songwriter)
- Simonetti, Claudio
- Simonetti, Mike
- Simoni, Edward
- Simoni, Paolo
- Simoninha
- Simoninha, Wilson
- simons, Aj
- Simons, Eva (Dutch singer & songwriter)
- Simons, Eva feat. Konshens
- Simons, Hein
- Simons, Keaton
- Simons, Matt
- Simons, Matt & Ayer, Chris
- Simons, Moisés
- Simons, Nat (Country-rock Spanish singer-songwriter)
- Simons, Scott (UK techno producer, member of Ultra DJ's)
- Simons, Scott (US singer/songwriter & pianist)
- Simons, Simone feat. Ayreon
- Simonsen, Rob (American score composer)
- Simony (Brazilian singer)
- SIMONY (French rapper)
- Simonz, Kelly, Blind Faith
- Simp Vader (New Zealand alternative/shoegaze band)
- SIMPIG
- Simpkin Project, The
- Simpkins, Nat
- Simpkins, Rev
- Simple Creatures (Mark Hoppus & Alex Gaskarth)
- Simple E
- Simple Gifts
- Simple Kid (Irish musician Kieran Macfeely)
- Simple Minds (Scottish rock band)
- Simple Minds feat. Tunstall, KT
- Simple Plan
- Simple Plan feat. Bedingfield, Natasha
- Simple Plan feat. Cuomo, Rivers
- Simple Plan feat. Gaskarth, Alex
- Simple Plan feat. K'naan
- Simple Plan feat. K’naan
- Simple Plan feat. Marie‐Mai
- Simple Plan feat. Nelly
- Simple Plan feat. Pundik, Jordan
- Simple Plan feat. R. City
- Simple Plan feat. Sean Paul
- Simple Plan feat. Simms, Juliet
- Simple Symmetry
- Simple, Andrew
- Simplefast
- Simpleton
- Simpletones (US late 1970s pop punk band)
- Simplified
- Simplifires (3 mexicans, 1 irish)
- Simplu (romanian pop band)
- Simply Chill
- Simply Red (English soul and pop band)
- Simply Saucer
- Simply Three
- Simplyd4rk (Groupe de metal undead français(nantes))
- Simpson (US hip‐hop artist)
- Simpson Allen
- Simpson, Alli
- Simpson, Ashlee
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