- Usher, Isabèl (Songwriter/vocalist from the Netherlands)
- Usher, Jessie T. & Proal, Aimée
- Usher, Lil Jon & Ludacris
- Usher, Madeleine
- Usher, Txarly
- Usher, Walker, Summer & 21 Savage
- Ushio, Kensuke
- Ushirogami Hikaretai
- Usi, Adam
- USK (German punk band)
- Uski's, The
- USKY (French rapper)
- Uslusoy, Umut
- Usma & Su Conjunto
- Usmonova, Yıldız
- Usmonova, Yulduz
- Usnea
- Uso to Chameleon
- usr/friendly
- USS (Ubiquitous Synergy Seeker)
- UssaR (Emmanuel Trouvé)
- Ustad Sultan Khan, K. S. Chitra
- Usted Señalemelo
- Ustinov, Peter
- Üstmamò
- Üstmamò feat. Europeiani
- Usual Suspects, The (trance, singles “The Love You Promised”, “Sunburn”)
- Usual, The
- Usud (Death Metal band from Zagreb, Croatia)
- Usura (spanish pop band)
- Ușurelu, Alexandra (Romanian Pop Singer)
- Usurp Synapse
- Usurper (US black/thrash metal band)
- Utada
- Utada, Hikaru (Japanese-American singer-songwriter)
- Utada, Hikaru & Arca
- Utada, Hikaru & Skrillex
- Utah (Danish band)
- UTAH (hip-hop / electronic)
- Utah (Electronic Duo from Argentina)
- Utah (Indie rock band from Troy, NY)
- Utah Carol
- Utah Jazz (UK musician Luke Wilson)
- Utah Saints
- Utah Saints vs. Drumsound & Bassline Smith
- Utama, Ant
- Utami, Trie
- Utangarðsmenn
- UtataP
- Utbult, Roland (Christian Singer/Songwriter & Politician)
- Ute til Lunch
- Uteligger, Ola
- Utero (Tokyo-based etherpop solo project)
- UTFO
- UTFO feat. Anthrax
- Utgé-Royo, Serge (singer-songwriter)
- Uthanda
- Uther Moads
- Uthup, Usha
- Uthup, Usha & Bhardwaj, Rekha
- Uthup, Usha, Bhardwaj, Rekha, Cerejo, Clinton & Castellino, Francois
- Utilize the Remains (New Zealand brutal death metal)
- Utkarsh Ambudkar (Rapper / actor)
- UTKF
- Utku, Hüma (fka R.A.N. / Roads at Night)
- Utmarken (hard rock/metal with Scandinavian folk music)
- UTO
- UTO feat. HSRS
- Utoku, Keiko (B.B.Queens & Mi‐Ke)
- Utopia (US progressive rock band led by Todd Rundgren)
- Utopia (Indonesian female-fronted band.)
- Utopia (UK Hi NRG on Almighty Records "Feel the Need in Me")
- Utopia (Russian drum & bass duo)
- Utopia (German krautrock band)
- Utopia (Banda brasileira)
- Utopia (New Zealand video game composer)
- Utopia Now
- Utopiae
- Utopians
- Utopiates, The
- Utópica Orquesta
- Utópico Amanecer (argentinian indie rock band)
- Utopie (french punk band)
- Utro (Post-punk from Russia)
- Utro
- Utsunomiya, Takashi
- UtsuP
- Uttal, Jai
- Uttal, Jai & Leinbach, Ben
- Uttal, Jai and the Pagan Love Orchestra
