- Urquhart, Felicity
- Urquijo, Álvaro
- Urquijo, Enrique
- Urquiza, Gilberto
- Urrutia, Jaime
- Ursa Major (Early 90s techno, Hans Hoppenbrouwers)
- Ursa Major (Cedarvale Park, Canada)
- Ursa Major (60's US heavy psych band (Dick Wagner))
- Urselle
- Ursin, Eeppi
- Ursina
- Ursine Vulpine (Frederick Lloyd)
- Ursiny, Dežo & Štrpka, Ivan
- Urskog
- Ursprung Buam
- URSS Bajo el Árbol (Mexican progressive rock band)
- URSS, La (Spanish punk)
- Úrsula (Ambient / Electroacoustic, Cadiz - Sevilla, Spain)
- Ursula 1000
- Ursull, Joëlle
- Ursus
- Ursus Factory (Finnish garage rock duo)
- Ursut
- Urszula
- Urszula i Budka Suflera
- Urthboy (Australian rapper)
- Urthboy feat. Burnett, Alexander
- Urthboy feat. Dyson, Mia
- Urthboy feat. Merriweather, Daniel
- Urthboy feat. Pearl, Mark
- Urthboy feat. Solo & Jimblah
- Urthboy feat. Texture Like Sun & Jones, Ev
- Urthboy feat. Tyrrell, Jane
- Urthboy feat. Tyrrell, Jane & Jimblah
- Urtz
- Uru (Japanese singer)
- Urusei Yatsura (Scottish lo-fi rock band)
- UrvTek
- Urwitz, David
- Urza (German funeral death/doom metal band)
- Urzah
- Urze De Lume
- US (hard rock, US, 70s)
- Us (Swedish duo featuring Geneva frontman Andrew Montgomery)
- Us As Effigies
- Us Baby Bear Bones
- US Rapper (US Rapper)
- Us the Duo
- Us, From Outside
- Us3
- Us3 feat. Rahsaan
- Us3 feat. Rahsaan & Presencer, Gerard
- US3R
- US5
- US69
- USA for Africa
- USA Freedom Kids
- USA Waste
- USA-European Connection (disco)
- USAF Heritage of America Band
- USAO
- USAO & Kubota, Shandy
- Usbeck, Maria
- USCB Allstars
- Uschi
- USE (Untitled Social Experiment)
- Use Me
- Used (featured artist on a Flosstradamus track)
- Used, The (US rock band)
- Used, The & My Chemical Romance
- Used, The feat. Barker, Travis
- Used, The feat. Butler, Jason Aalon
- Used, The feat. Caleb Shomo
- Used, The feat. Hoppus, Mark
- Useless ID (Israeli punk band)
- Useless Wooden Toys
- Useless Youth (Mexican alternative band)
- Useme (Modern pop-rock band)
- usephasan
- User (Vancouver industrial/post-rock guitarist)
- User (Swedish rock band from Örebro)
- User2222 (aka Dead Bart)
- USERx (Matt Maeson & Ross Fitzgerald project)
- Usha (Telugu playback singer)
- Usher (R&B singer-songwriter Usher Raymond Ⅳ)
- Usher & Keys, Alicia
- Usher & Pitbull
- Usher & will.i.am
- Usher & Zaytoven
- Usher feat. ASAP Rocky
