- Urnscent (Iranian Doom Metal Band)
- Uroboros (Japanese Group)
- Urouna, Emmanuel (Nigerian Singer and Songwriter)
- Uroyan
- Uroyan & Tony Music (Reggaeton Duo)
- Uroyan feat. Armakahn
- Uroyan feat. Borges, Charlie
- Uroyan feat. JC
- Uroyan feat. Tony Music
- Urquhart, Felicity
- Urquijo, Álvaro
- Urquijo, Enrique
- Urquiza, Gilberto
- Urrutia, Jaime
- Urrutia, Jaime & Bunbury
- Ursa Major (Early 90s techno, Hans Hoppenbrouwers)
- Ursa Major (Cedarvale Park, Canada)
- Ursa Major (60's US heavy psych band (Dick Wagner))
- Ursa Major (illymation)
- Urselle
- Ursin, Eeppi
- Ursina (Swiss pop)
- Ursine Vulpine (Frederick Lloyd)
- Ursine Vulpine & Annaca
- Ursiny, Dežo
- Ursiny, Dežo & Štrpka, Ivan
- Urskog
- Ursprung Buam
- URSS Bajo el Árbol (Mexican progressive rock band)
- URSS, La (Spanish punk)
- Ursu, Andrei (f.k.a. WRS)
- Úrsula (Ambient / Electroacoustic, Cadiz - Sevilla, Spain)
- Ursula 1000
- Ursull, Joëlle
- Ursus
- Ursus Factory (Finnish garage rock duo)
- Ursut
- Urszula
- Urszula i Budka Suflera
- Urthboy (Australian rapper)
- Urthboy & Tyrrell, Jane
- Urthboy feat. Blackman, Bertie
- Urthboy feat. Burnett, Alexander
- Urthboy feat. Dyson, Mia
- Urthboy feat. Hau & Muph
- Urthboy feat. Merriweather, Daniel
- Urthboy feat. Pearl, Mark
- Urthboy feat. Puru, Kira
- Urthboy feat. Solo & Jimblah
- Urthboy feat. Texture Like Sun & Jones, Ev
- Urthboy feat. Tyrrell, Jane
- Urthboy feat. Tyrrell, Jane & Jimblah
- Urtz
- Uru (Japanese singer)
- Urusei Yatsura (Scottish lo-fi rock band)
- UrvTek
- Urwitz, David
- Ury Summers (Los Angeles pop-punk)
- Urza (German funeral death/doom metal band)
- Urzah
- Urze De Lume
- US (Dutch prog band, post Saga)
- Us As Effigies
- Us Baby Bear Bones
- US Rapper (US Rapper)
- Us the Duo
- Us, From Outside
- Us3
- Us3 feat. Rahsaan
- Us3 feat. Rahsaan & Presencer, Gerard
- Us3 feat. Rahsaan and Presencer, Gerard
- US3R
- US5
- US69
- USA for Africa
- USA Freedom Kids
- USA Waste
- USA-European Connection (disco)
- USAF Heritage of America Band
- USAO
- USAO & Kubota, Shandy
- Usart, Roger
- Usbeck, Maria
- USCB Allstars
- Uschi (Argentinian singer)
- USE (Untitled Social Experiment)
- Use Me
- Used (featured artist on a Flosstradamus track)
- Used (Belgian drum 'n bass producer Jo Eelen)
- Used, The (US rock band)