- iI
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- IAMIan
- IanIbr
- IbrIce
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- IceIco
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- ItIt
- ItIva
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- IvyIYA
- IyaIZI
- IZIIzz
- Irina & Vilkkumaa, Maija
- Irina Barros (Kizomba)
- Irino, Miyu
- Irio, Juan & Uzal, Sofía
- Iriondo, Lourdes
- Iriondo, Silvia (Argentine ethnomusicologist, composer and singer)
- Iris (Texan synthpop band)
- IRIS (Romanian rock band)
- Iris (A pop / rock british group)
- Iris (Belgian Singer Laura van den Bruel)
- iRis (Idol group)
- IRIS (Portuguese Rock band)
- Iris (Iris Woo; Malaysian singer active in Japan)
- Iris (Australia)
- Iris (Montreal-based pop singer/drummer)
- Iris (shoegaze band from Toronto, Canada)
- Iris (alternative rock on Bubble Core Records)
- IRIS (Czech pop / singer-songwriter)
- Iris & Arm (French hip-hop band)
- Iris & Rose: "Wild & Thorny"
- Iris Bevy
- Iris Doe (Project from Jeffrey Cain of The Church)
- Iris Liu (iii(Iris Liu))
- Iris Lune
- Iris Temple
- Iris, Donnie
- İris, Esin
- iRis.EXE
- Irisa
- IRISÉ
- Iriser, ANEXIA, Shock, Billy
- Iriser, Roland, Stefre, ANEXIA feat. Ornimental
- Irish All-Stars
- Irish Basement
- Irish Brigade, The (Irish Rebel Band from Co. Tyrone (Northern Ireland))
- Irish Ceili Band, The
- Irish Coffee (Belgian hard rock band)
- Irish Descendants, The
- Irish Drovers
- Irish Front, The (Death metal band)
- Irish Handcuffs
- Irish Moutarde
- Irish Mythen
- Irish Roses
- Irish Rovers, The (Irish Canadian folk rock aka The Rovers)
- Irish Stew of Sindidun
- Irish Tenors, The
- Irish Women in Harmony
- Irist
- Irk (mathcore / noise rock)
- Irko (French rapper)
- Irko & amne
- Irko & Meel B
- Irl Sam
- Irma (Swedish pop singer)
- Irma (Cameroun/French singer)
- Irma & M
- Irma & Youssoupha
- Irma Thomas & the Professionals (New Orleans Blues)
- Irma Vep
- Irma y Oswado
- Irmak, Sinem
- Irmão Victor
- Irmãos Bertussi
- Irmãos Catita
- Irmãos Verdades
- Irmãs de Pau
- Irminsul
- Irn Mnky X Beastie Boys
- Irnini Mons
- Iro (Brooklyn, NY, United States)
- Irodorimidori
- IROH (Russian rapper)
- iroha (English rock band, bassist from Jesu)
- iroha(sasaki) (Vocaloid producer)
- iRokkout
- Irokz
- IRON
- Iron & Wine
- Iron & Wine & Bridwell, Ben
- Iron & Wine & Bridwell, Ben
- Iron & Wine and Calexico
- Iron & Wine feat. I’m With Her
- Iron Age
- Iron Angel
- Iron Bell Music
- Iron Boots (Hardcore band from Virginia)
- Iron Brigade
- Iron Butterfly
- Iron Chic