- Ismajli, Adelina
- Ismen (Swedish hip hop)
- Ismeros Arcok
- Ismo Alanko Säätiö
- Ismo Alanko Teholla (Ismo Alanko and Teho Majamäki's project.)
- Ismo, Lijpe x
- Iso H
- ISO Indies
- Iso, King (Tarrel C. Gulledge)
- Iso, King feat. Daylyt
- Iso, King feat. King Kash & Snake Lucci
- Isoir, André (organist)
- Isolate.exe (phonk music)
- Isolated (~Johannes Gräf & Marcel Güntner)
- Isolated Corners
- Isolated Youth
- Isolation (Germany / Black/Doom Metal)
- Isolation Berlin
- Isolation Years
- Isolation, In
- Isole
- Isolée
- Isomer, Sin
- isomonstrosity
- Ison & Fille
- Ison & Fille feat. Amin
- Ison & Fille feat. Amin & Sseruwagi, Mogge
- Ison & Fille feat. Fre & Sseruwagi, Mogge
- Ison & Fille feat. Meles, Nebay & Rosh
- Ison & Fille feat. Zarate, Michelle
- IsOokSchitterend
- Isosine
- Isostatic (ambient project aka Sean Costello)
- Isotalo, Suvi
- Isotope
- Isotope Soap
- Isotopes
- Isotopes (Sydney, Aus. Melodic Hardcore)
- Isoul8
- Isović, Safet (Bosnian Folk singer)
- Ispolins
- Isproject
- Israel (1990s US Christian pop)
- Israel (probably australian hiphop)
- Israel & New Breed
- Israel & New Breed feat. Adams, Yolanda
- Israel & New Breed feat. McReynolds, Jonathan
- Israel & New Breed feat. T-Bone
- Israel & New Breed feat. Tribbett, Tye
- Israel & Rodolffo
- Israel & Rodolffo & Juliette
- Israel B
- Israel B & Lowlight
- Israel Fernández y Diego del Morao
- Israel Novaes
- Israel Philharmonic Orchestra
- Israel Vibration
- Israel, Dan
- Israel, Jake
- Israel, Joseph
- Israelites, The (USA Christian Ska)
- Israelsson, Karl-Erik
- Issa (Norwegian Singer)
- Issa Gold (The Underachievers)
- Issa, Sámer
- Issaba (Rappeur fr)
- Issac, Barry
- Issam (Moroccan rapper)
- Isserley (witch house)
- ISSUE (US rap artist)
- Issues
- ist
- Ist Ist
- Istanbul Oriental Ensemble
- İstanbul Trip
- Istapp
- Isten Háta Mögött
- Istentales
- Istoria (Istoria Band from Malaysia)
- Istrefi, Era
- István, Tabáni
- İsyan Tetick
- Isyss
- It Bites
- It Boys!
- It Dies Today
- It It Anita (Belgian noiserock band)
- It Lies Within
- It Lives, It Breathes
- It Looks Sad.