- XOMG POP!
- Xomu
- XONARA
- Xonia & Balvin, J
- XONOR
- xooos
- Xopowo
- XOR (US electronic musician from Asheville, NC)
- Xorcist
- Xordia
- Xori
- Xose Lois Romero & Aliboria
- Xoth (Technical Death/Black/Thrash Metal from Seattle)
- xotox
- XOV (Swedish singer-songwriter)
- XOX (Japanese group "Kiss Hug Kiss")
- XOXO (Filipino girl group)
- XOXO Feat. Bellanova
- XOXO's, The
- Xoxocapa, Trío
- XP Voodoo
- XP-30
- XP8
- Xpansions (known for ‘Move Your Body’)
- Xpansions 95 (AKA Xpansions)
- Xpansions 95
- XPDC
- Xperience (US rapper, a.k.a. XP)
- Xperiment (aggrotech band from Spain)
- Xploding Plastix
- Xploding Plastix feat. Cracknell, Sarah
- Xplore Yesterday
- Xplosn (edm artist)
- XPQ-21
- XpresidentX
- xPropaganda (Claudia Brücken und Susanne Freytag, former 'Propaganda')
- Xquè? (Makina Club from Calella de Palafrugell, Girona)
- Xquizit, DJ
- Xquizit, DJ feat. Hilberts, Tim
- XRaidX
- Xramovi, Misha
- Xravial & azulaqueen
- XRay5, The (LA post-punk band)
- Xrchy
- XReal
- xRepresentx (American straight edge hardcore band)
- Xriz
- XRP Bags
- XRUSTALIC
- XRUSTALIC & ioneweb
- XRUSTALIC & nttrl
- XS Project
- XS Project & Life of Boris
- XSakara
- XSARA
- XsavioR
- Xscape
- xServitudex
- XSI (Psytrance project from France)
- XSOLEIL (NIJISANJI EN VTuber group)
- Xstasia
- Xstitch (trapmetal)
- XT
- Xtasy (Spanish hard rock band)
- Xtatik
- XTC (English rock band)
- Xtha
- xthedoc
- xthedoc feat. Jordan Parat
- XTIE (Hong Kong Solo Artist)
- XTINA GG
- xtinto (Portuguese Rapper)
- xtinto & price, benji
- XTM (Catalan dance music act;Brothers Xasqui and Toni Ten)
- XTM & Chucky, DJ
- XTM & DJ Chucky
- Xtortion Audio
- XTR Human
- Xtract (UK punk band from Sheffield)
- XtraGreen
- Xtreme (US bachata group)
- Xtreme feat. Adrienne Bailon
- Xtreme Kids
- Xtreme Kids (Christian music group)
- Xtreme Team (Italian crew)
- xtrevort (rapper from boston)
- xTRiPx
- XTRMST
- Xtrullor
- Xtruppaw
