- Xis
- XisForEyes
- XIT (native American rock band)
- Xiu Xiu (American experimental band)
- XIUMIN (EXO)
- Xiupill (Icelandic experimental pop trio)
- XIV Dark Centuries
- XIXA (Band (Brian Lopez and Gabriel Sullivan))
- xKINGx (Downtempo, Metal)
- xKore
- Xkrude
- XL5 (Finnish group)
- xLooking Forwardx
- XLR (french hip hop)
- Xlson137 (UA rapper)
- Xmal Deutschland
- XMASwu
- XMawja (software engineer)
- xMeans to an Endx (Hardcore from Winnipeg)
- XMH
- xNOMADx (Vegan Edge Metal from the Northeast)
- XO (US rapper, member of Diamond District, aka Uptown XO)
- XO (Californian rock band)
- XO (Producer, Staffordshire, UK)
- XO (California shoegaze band)
- xo purp
- XO TEAM
- XO Xuded
- XO‐IQ
- XO‐IQ feat. Slachta, John‐Alan
- XO, MoneyBaby & Reddy, PullUp
- XOAN
- XoBrooklynne
- XOC (Jason Cox)
- Xoch
- Xochimilcas, Los
- XODIAC (South Korean boy group)
- xojira
- Xolo (L.A.-based dream pop duo)
- Xolotl (USA, Black Metal)
- XOMG POP!
- Xomu
- xooos
- Xorcist
- Xordia
- xotox
- XOV (Swedish singer-songwriter)
- XOXO's, The
- Xoxocapa, Trío
- XP Voodoo
- XP8
- Xpansions (known for ‘Move Your Body’)
- Xpansions 95 (AKA Xpansions)
- XPDC
- Xperience (US rapper, a.k.a. XP)
- Xperiment (aggrotech band from Spain)
- Xploding Plastix
- Xploding Plastix feat. Cracknell, Sarah
- Xplore Yesterday
- XPQ-21
- xPropaganda (Claudia Brücken und Susanne Freytag, former 'Propaganda')
- Xquizit, DJ
- Xquizit, DJ feat. Hilberts, Tim
- XRaidX
- Xramovi, Misha
- XRay5, The (LA post-punk band)
- xRepentancex
- xRepresentx (American straight edge hardcore band)
- Xriz
- XRP Bags
- XS Project
- XSakara
- XSARA
- Xscape
- xServitudex
- XSI (Psytrance project from France)
- Xstasia
- XT
- Xtatik
- XTC (English rock band)
- XTIE (Hong Kong Solo Artist)
- XTM (Catalan dance music act;Brothers Xasqui and Toni Ten)
- XTM & Chucky, DJ
- XTM & DJ Chucky
- Xtortion Audio
- Xtract (UK punk band from Sheffield)
- Xtreme (US bachata group)
- Xtreme feat. Houghton, Adrienne
- Xtreme Kids
- Xtreme Kids (Christian music group)