- XLOV
- XLR (french hip hop)
- XLR8 (Filipino band)
- Xlson137 (Russian rapper)
- XLVR
- XM, Antonia (runs Ashida Park label)
- Xmal Deutschland
- XMASwu
- XMawja (software engineer)
- xMeans to an Endx (Hardcore from Winnipeg)
- Xnghan&Xoul
- xNOMADx (Vegan Edge Metal from the Northeast)
- xnti
- XO (US rapper, member of Diamond District, aka Uptown XO)
- XO (Californian rock band)
- XO (California shoegaze band)
- xo (electropop artist)
- XO (British girl group)
- Xo Man
- Xo Mo
- xo purp
- xo purp & nash.ovi
- xo sad
- xo sad & unheard
- XO TEAM
- XO Xuded
- XO‐IQ
- XO, MoneyBaby & Reddy, PullUp
- XO, Noah
- XO1
- XOAN
- Xoán Curiel
- XoBrooklynne
- Xoch
- Xochimilcas, Los
- XODIAC (South Korean boy group)
- xofilo (Hyperpop artist affiliated with Flex Entertainment)
- xofilo & 1Psion
- xofilo & Mutatty
- XoForbidden
- XoForbidden, Wames, James
- xojira
- Xolidayboy
- xolilsauce feat. Caine$tiff
- Xolo (L.A.-based dream pop duo)
- Xolotl (USA, Black Metal)
- XOMG POP!
- Xomu
- Xonia & Balvin, J
- XONOR
- xooos
- XOR (US electronic musician from Asheville, NC)
- Xorcist
- Xordia
- Xori
- Xose Lois Romero & Aliboria
- xotox
- XOV (Swedish singer-songwriter)
- XOX (Japanese group "Kiss Hug Kiss")
- XOXO (Filipino girl group)
- XOXO Feat. Bellanova
- XOXO's, The
- Xoxocapa, Trío
- XP Voodoo
- XP-30
- XP8
- Xpansions (known for ‘Move Your Body’)
- Xpansions 95 (AKA Xpansions)
- Xpansions 95
- XPDC
- Xperience (US rapper, a.k.a. XP)
- Xperiment (aggrotech band from Spain)
- Xploding Plastix
- Xploding Plastix feat. Cracknell, Sarah
- Xplore Yesterday
- Xplosn (edm artist)
- XPQ-21
- xPropaganda (Claudia Brücken und Susanne Freytag, former 'Propaganda')
- Xquè? (Makina Club from Calella de Palafrugell, Girona)
- Xquizit, DJ
- Xquizit, DJ feat. Hilberts, Tim
- XRaidX
- Xramovi, Misha
- XRay5, The (LA post-punk band)
- Xrchy
- XReal
- xRepresentx (American straight edge hardcore band)
- Xriz
- Xriz & NeURO
- XRP Bags
