- 50 Foot Wave
- 50 Guitars of Tommy Garrett, The
- 50 hertz
- 50 Kaitenz, The
- 50 Lions
- 50 Year Storm
- 50/50 Twin (Houston rapper)
- 500 mil
- 500 Miles to Memphis
- 500$Fine
- 5000 Volts
- 501 (dubstep producer Jussi Leväsalmi)
- 501 (latin gangsta rap)
- 501Bryze
- 502s, The
- 504 Boyz
- 5050
- 5050 El Barret (Narco Rapper)
- 509 BMG
- 509 BMG feat. Auto*
- 509-E
- 50landing
- 50mMidas
- 51 Black Super
- 51 Grados
- 51 Peg (industrial rock band)
- 51, Method
- 51.50 Illegally Insane
- 510 (Rock band from Indonesia)
- 51koodia
- 51st Avenue
- 52 Factorial
- 52 Hertz (German Emo band)
- 52nd Regimental String Band, The
- 52nd Street (UK jazz-funk band)
- 53 Days
- 54 Reasons
- 54 Seconds
- 54 Ultra
- 54-40
- 54daysathome
- 54KG
- 54th Platoon
- 55 Cancri e (Sara Hausenkamp)
- 55 Escape
- 55, BLK (Indonesia Musician, Rapper, Songwriter)
- 555 (Marco Comis)
- 5566
- 55ymtk
- 56 Hamburguesas
- 5606
- 562 (Hardcore band from Chile)
- 56k feat. Bejay
- 57 Grados
- 57Danka (German rapper)
- 58 (project of Nikki Sixx & Dave Darling)
- 59 Shop
- 59 Times the Pain
- 5ª Estacion, La
- 5admin
- 5AM (electronic music artist Samuel Andrus from California)
- 5AM (US rapper)
- 5angels
- 5Bugs
- 5c Deposit
- 5diez (Belarusian alternative band)
- 5EB
- 5etra
- 5ft High & Rising (Metalcore Band from Hannover, Germany)
- 5HONUFF
- 5hy
- 5hy & Sence
- 5idelity
- 5ive (progressive metal band from Boston, MA)
- 5ive (christian rapper Craig James)
- 5ive (5ive from Me and My Brother)
- 5ive's Continuum Research Project
- 5ivlover
- 5K HD
- 5L (digicore artist)
- 5L & snackrunner
- 5LOKO
- 5Loops
- 5Loops & Genka
- 5Loops, s'Poom & Chalice
- 5LOVER
- 5M
- 5mewmet
- 5MIINUST
- 5MIINUST & Puuluup
