- 2amtheband
- 2ARA
- 2B PENCILS
- 2Baba (2Face Idibia)
- 2BiC
- 2ble Jay
- 2BYG
- 2CELLOS (Croatian cellist duo)
- 2Cellos
- 2CELLOS feat. Ferreira, Sky
- 2CELLOS feat. John, Elton
- 2CELLOS feat. Rivera, Naya
- 2CELLOS feat. Zucchero
- 2CELLOS, London Symphony Orchestra
- 2Cents
- 2charm (indie house techno sleaze dubstep baile g00ner pop)
- 2cheesemilkshake
- 2cztery7
- 2cztery7 feat. Małolat
- 2cztery7 feat. Pacak, Piotr
- 2cztery7 feat. Pelson
- 2cztery7 feat. Sosh
- 2D (Indonesian pop group)
- 2DB (Simon "Bassline" Smith & Andy Wright)
- 2DCAT
- 2DCAT & HAEZL
- 2econd Class Citizen feat. Ceschi
- 2ersitz
- 2ersitz & Haller
- 2EYES (South Korean girl group)
- 2Faces (canadian hip hop)
- 2far2jump
- 2Fast 4You
- 2FeetBino
- 2fox
- 2fox feat. Nandi
- 2Frères (Quebec folk duo)
- 2Friends
- 2Gether
- 2hermanoz
- 2hollis
- 2Hooks (Composers/Producers for Film & TV)
- 2Hounds
- 2Hurt (Italian band)
- 2i, Lil
- 2Icons
- 2K (aka The KLF)
- 2KBABY
- 2KBABY & Marshmello
- 2KBABY feat. G Herbo
- 2KBABY feat. Lil Durk
- 2KBABY feat. YFN Lucci
- 2Kvėpavimas (Lithuanian dance‐pop artist)
- 2Kvėpavimas & Bäsello
- 2Kvėpavimas × Adrina
- 2Kvėpavimas ft. Iglė
- 2LADE (German rapper)
- 2lane (Mozambican DJ)
- 2LATE
- 2loop (Deep House by Igor Matsagorov)
- 2manydjs
- 2Mex
- 2Mex feat. Awol One
- 2Mex feat. Murs & Ariano
- 2Minds (Psychedelic Trance duo brothers Shauli Ifrah & Miki Ifrah)
- 2NB
- 2ND (US rock / metal)
- 2nd Best
- 2nd Chapter of Acts
- 2nd Exit (Lester Duval & Alfa Mist)
- 2nd Exit & Thomas‐Dyke, Kaya
- 2nd Face
- 2nd Gen
- 2nd Generation Wu
- 2nd Grade
- 2nd II None (Rap duo from Compton, Los Angeles)
- 2nd II None feat. AMG & Quik, DJ
- 2nd Life, Svniivan & Salvo
- 2nd Moon
- 2nd Nature (Ruud Van Rijen)
- 2nd Nature (Male R&B quartet from Seattle, Washington.)
- 2nd Roof (italian hip hop producers)
- 2nd Shift
- 2nd South Carolina String Band
- 2nd Today (alt-rock from Greensboro, NC)
- 2NE1
- 2NU
- 2Pac (US rapper)
- 2Pac & Clinton, George
- 2Pac & Danny Boy
