- EE
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- Esperanza (US Latin/Flamenco)
- Esperanza (Brazillian rock band)
- Esperanza de Vida (Spanish Christian music duo)
- Esperanza De Vida (Christian Group)
- Esperanza, Lord (French rapper)
- Esperanza, Lord & Lefa
- Esperanza, Lord & Majeur Mineur
- Esperit! (Experimental musician Dalmau Boada)
- Espermachine
- Espers
- Espeseth, Dylan
- Espiiem (French studio manager ex-hip hop artist)
- Espil, An (Argentine musician)
- Espina
- Espíndola, Tetê
- Espineli
- Espinosa, Anna Maria
- Espinosa, Eddie
- Espinosa, Eden
- Espinosa, Luis Enrique
- Espinosa, Marie
- Espinosa, Pablo
- Espinosa, Ricky
- Espinoza Paz (Regional Mexican singer-songwriter)
- Espinoza, Roger
- Espionage (Australian Heavy Metal Band based in Melbourne)
- Espionne, The
- Espiritu
- Espíritu (Argentine prog rock band)
- Espiritu Andino
- Espiritu Olimpico (Uruguayan band)
- Espíritus, Los
- Espíritus, Los & Melingo, Daniel
- Espíritusanto
- Esplendor Geométrico (industrial/experimental noise group)
- Espoir pour Haïti
- Espoirs de Coronthie
- Espoo Big Band
- Esposito, Ben
- Esposito, Davide
- Esposito, Joe
- Esposito, John L. (academic)
- Espósito, Lali
- Esposito, Tony
- Esprit D’Air (Japanese alternative metal band)
- Esprit du Clan, L’
- Espumas y Terciopelo
- Espumita (garage rock from Guayaquil, Ecuador)
- Esquires, The (US R&B group, famous for "Get on Up")
- Esquirols
- Esquivel
- Esquivel and His Orchestra
- Esquivel, Juan Garcia
- Esquivel, Juan García (Mexican band leader, pianist & film/TV composer)
- Esquivel, Laura Natalia (Argentine actress and singer)
- Esquivel, Sergio (mexican singer)
- Esquizitos, Los
- Esquys
- Esreverse
- Essaïdi, Sofia
- Essaie pas
- Essam, Ramy
- Essco, Billie
- Esse, Christopher (US Prog Artist)
- esseca (Filipino Artist)
- Essed, Osei
- Essence (Danish metal band)
- Essence (UK hard trance duo, released “The Promise”)
- Essence (synthpop/Euro disco duo, single “Kahlua Sun”)
- Essence All Stars, The
- Essence of Datum
- Essence of Mind
- Essence of Sorrow
- Essence, The (Dutch dark wave/gothic rock band)
- Essence, The (80s goth synthpop)
- Essenger (Synthwave from Kansas City, Missouri)
- Essenger & PYLOT
- Essenger & Young Medicine
- Essenger feat. Lexi Norton
- Essenger feat. Midnight, The
- Essenger feat. Scandroid
- Essential Logic
- Essentialists, The
- Essenza (Heavy Metal, Italy)
- Esser
- ESSERE (Octavian Tilvar)
- Essex Green, The (US indie rock band)
- Essex, David
- Essex, The (60s R&B vocal group)
- Essexx
